4-Methoxy-4-(3-hydroxy-trans-prop-1-enyl)tetrahydropyran → HCID 67825144, compound

HRID 326235Notes

Reaction equation

HRID 326235 reaction equation
[OH:1][CH2:2]/[CH:3]=[CH:4]/[C:5]1([O:11][CH3:12])[CH2:10][CH2:9][O:8][CH2:7][CH2:6]1.CC(C)=[O:15].OS(O)(=O)=O.O=[Cr](=O)=O>CC(C)=O>[CH3:12][O:11][C:5]1(/[CH:4]=[CH:3]/[C:2]([OH:15])=[O:1])[CH2:6][CH2:7][O:8][CH2:9][CH2:10]1

Participants

4

Reactant 2

HCID 151990644-Methoxy-4-(3-hydroxy-trans-prop-1-enyl)tetrahydropyranHCID 131709961Jones' reagent

Product 1

HCID 67825144HCID 67825144, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

4-(3-hydroxy-trans-prop-1-enyl)-4-methoxy-tetrahydropyran (175 mg, 1.02 mmol), prepared as in Example 1, steps 1-3, was oxidized to the corresponding carboxylic acid by treatment with a slight excess of Jones reagent in cold acetone.

Sources & evidence

ORD record
ord-fab96b327876439792a4671e4fdfa7bf
Source dataset
uspto-grants-1993_12
Patent number
US05268379

Reaction notes

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