Bromine → HCID 19092144, compound

HRID 326241Notes

Reaction equation

HRID 326241 reaction equation
[C:1]([C:4]1[CH:14]=[CH:13][C:7]2[CH2:8][C:9](=[O:12])[NH:10][O:11][C:6]=2[CH:5]=1)(=[O:3])[CH3:2].[Br:15]Br>C(Cl)Cl>[Br:15][CH2:2][C:1]([C:4]1[CH:14]=[CH:13][C:7]2[CH2:8][C:9](=[O:12])[NH:10][O:11][C:6]=2[CH:5]=1)=[O:3]

Participants

4

Reactant 2

HCID 24408BromineHCID 19092089HCID 19092089, compound

Product 1

HCID 19092144HCID 19092144, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

0.01 mol of 7-acetylbenzoxazinone, described in Application EP 223,674, is dissolved in 100 cm3 of methylene chloride. 0.011 mol of bromine is added dropwise and with stirring via a dropping funnel, and stirring is maintained for 13 hours. The mixture is filtered and evaporated to dryness and the residue is recrystallized.

Workup

  1. stirringstirring
  2. temperatureis maintained for 13 hours
  3. filtrationThe mixture is filtered
  4. customevaporated to dryness
  5. customthe residue is recrystallized

Sources & evidence

ORD record
ord-1d5d9a81a0e94533a5637b80fd592ef2
Source dataset
uspto-grants-1993_12
Patent number
US05268381

Reaction notes

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