HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diketene → HCID 19967135, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diketene | HCID 12661 | — |
| Reactant | 4-Imidazol-1-ylmethylphenylamine | HCID 1265319 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 19967135 | HCID 19967135 | 74.8% |
Reaction Steps
To a stirred solution of 10 parts of 4-[(1H-imidazol-1-yl)methyl]benzenamine in 180 parts of 1,2-dichloroethane were added dropwise 3.9 parts of 4-methylene-2-oxetanone. After stirring for 1/2 hour at room temperature, the precipitate was filtered off, washed with 1,2-dichloroethane and dried, yielding 9.8 parts (74.8%) of N-[4-(1H-imidazol-1-ylmethyl)phenyl]-3-oxobutanamide; mp. 175° C. (interm. 57).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05268380 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-336eae54dc1a4aa695ce590de00968d2 |
| Source note | uspto-grants-1993_12 |