HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrabromophthalic anhydride → 2,3,4,5-Tetrabromo-6-[(4-chloro-2-fluoro-5-isopropoxycarbonyl-phenyl)carbamoyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrabromophthalic anhydride | HCID 12443 | — |
| Reactant | Propan-2-yl 5-amino-2-chloro-4-fluorobenzoate | HCID 13519894 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2,3,4,5-Tetrabromo-6-[(4-chloro-2-fluoro-5-isopropoxycarbonyl-phenyl)carbamoyl]benzoic acid | HCID 507315 | — |
Reaction Steps
Tetrabromophthalic anhydride (6.67 g, 0.014 mole) and 1-methylethyl 5-amino-2-chloro-4-fluorobenzoate (3.33 g, 0.014 mole) were heated to reflux with stirring in about 150 ml of toluene, then left overnight at room temperature. Filtration of the reaction mixture gave the title compound, m.p. 160°-165° C. (decomp.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05268389 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-8055ea95a4f246ebb0c3db129877e53e |
| Source note | uspto-grants-1993_12 |