HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrachlorophthalic anhydride → 2,3,4,5-Tetrachloro-6-[(4-chloro-3-isopropoxycarbonyl-phenyl)carbamoyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrachlorophthalic anhydride | HCID 8326 | — |
| Reactant | Isopropyl 5-amino-2-chlorobenzoate | HCID 369590 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2,3,4,5-Tetrachloro-6-[(4-chloro-3-isopropoxycarbonyl-phenyl)carbamoyl]benzoic acid | HCID 503277 | 70% |
Reaction Steps
A mixture of tetrachlorophthalic anhydride (2.97 g, 0.010 mole), 1-methylethyl 5-amino-2-chlorobenzoate (2.22 g, 0.010 mole) and toluene (100 ml) was heated slowly to reflux with stirring, then left overnight at room temperature. Filtration of the reaction mixture gave the title compound, m.p. 178°-179° C. (3.45 g, 70% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05268389 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-04dd752ccf414eb685ac6e3834415e2e |
| Source note | uspto-grants-1993_12 |