HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Propanone, 3-(dimethylamino)-1-phenyl-, hydrochloride (1:1) → 3-(Dimethylamino)-1-phenyl-1-propanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Propanone, 3-(dimethylamino)-1-phenyl-, hydrochloride (1:1) | HCID 92844 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-(Dimethylamino)-1-phenyl-1-propanone | HCID 77042 | 95.3% |
Reaction Steps
3-Dimethylaminopropiophenone hydrochloride (20 g) was treated with aqueous sodium bicarbonate solution in dichloromethane. The layers were separated and the organic phase was dried over anhydrous magnesium sulfate, filtered, and the filtrate was evaporated to provide 15.8 g of 3-dimethylaminopropiophenone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05268468 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-8405d6c06e7a480280c47c4f322f1fd8 |
| Source note | uspto-grants-1993_12 |