HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → Ethyl 7-chloro-2-oxoheptanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Ethyl 7-chloro-2-hydroxyiminoheptanoate | HCID 73432769 | — |
| Product | Ethyl 7-chloro-2-oxoheptanoate | HCID 3018793 | — |
Reaction Steps
The solution of ethyl 7-chloro-2-hydroxyiminoheptanoate [III-1] in toluene obtained in Example 9 (without being concentrated) is added dropwise into 36 % aqueous formalin solution, and thereto is added sulfuric acid. The mixture is warmed, and further thereto is added water. The organic layer is separated, neutralized, washed with water, and concentrated under reduced pressure to give ethyl 7-chloro-2-oxoheptanoate [I-1].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05268501 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-1ae6b59943d8405dbe6e0360f80f1e9d |
| Source note | uspto-grants-1993_12 |