反应详情

A mixture of N,N'-dimethylethylene-diamine (25 g) and 2-chloropyridine (1.3 g) is warmed at 85° with stirring for 18 h. The excess dimethylethylenediamine is removed by distillation at reduced pressure. The distillation residue is distributed between ethyl acetate (150 ml) and water (100 ml). The organic phase is separated, dried over sodium sulfate and the organic solvent removed under reduced pressure to give the title compound.

1. temperatureis warmed at 85°
2. customThe excess dimethylethylenediamine is removed by distillation at reduced pressure
3. customThe organic phase is separated
4. dry with materialdried over sodium sulfate
5. customthe organic solvent removed under reduced pressure