HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonic Acid → HCID 86745584, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonic Acid | HCID 6395 | — |
| Reactant | HCID 14307778 | HCID 14307778 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86745584 | HCID 86745584 | — |
Reaction Steps
17α-Hydroxy-21-[4-(2-pyridinyl)-1-piperazinyl]pregna-4,9(11)-diene-3,20-dione (Example 1) is dissolved in methanol and treated with methane sulfonic acid (0.224 g). The solution is concentrated and the residue is crystallized from hot methanol and ethyl acetate to give a first crop of the title compound. A second crop of the mesylate is isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05268477 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-7f09b8a92df441e3872ab1bdc98cdc1a |
| Source note | uspto-grants-1993_12 |