Thiophenol → HCID 15730005, compound

HRID 326556Notes

Reaction equation

HRID 326556 reaction equation
[NH2:1][C:2]1[N:7]2[N:8]=[C:9]([C:11]3[S:12][CH:13]=[CH:14][CH:15]=3)[N:10]=[C:6]2[N:5]=[C:4]([S:16][CH3:17])[N:3]=1.[C:18]1(S)[CH:23]=[CH:22]C=[CH:20][CH:19]=1>>[NH2:1][C:2]1[N:7]2[N:8]=[C:9]([C:11]3[S:12][CH:13]=[CH:14][CH:15]=3)[N:10]=[C:6]2[N:5]=[C:4]([S:16][C:17]2[CH:22]=[CH:23][CH:18]=[CH:19][CH:20]=2)[N:3]=1

Participants

3

Reactant 2

HCID 7969ThiophenolHCID 15730000HCID 15730000, compound

Product 1

HCID 15730005HCID 15730005, compound

Procedure

Using a similar procedure to that described in Example 2 but starting from 7-amino-5-methylthio-2-(2-thienyl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine and using thiophenol, there was obtained 7-amino-5-phenylthio-2-(2-thienyl)-[1,2,4]triazolo[1,5-a][1,3,51triazine as a solid, m.p. >300° C. (decomposition); microanalysis, found: C, 51.9; H, 3.1; N, 25.6%; C14H10N6S2 requires: C, 51.5; H, 3.1; N, 25.8%; NMR 7.20(dd, 1H, thienyl-4H), 7.4-7.8(complex, 1H, phenyl-H, thienyl-3H,5H) and 8.83(d, 2H, NH2).

Sources & evidence

ORD record
ord-5fc8b239f2aa4d018232a6541b75f81d
Source dataset
uspto-grants-1993_12
Patent number
US05270311

Reaction notes

Loading…