Sodium Hydroxide → HCID 14842717, compound

Participants

Reaction Steps

Treatment of methyl 5-ethyl-4-oxo-1,4-dihydroquinoline-2-carboxylate (0.61 g) with sodium hydroxide (0.42 g), as described in Example 1c, gave 5-ethyl-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (0.34 g), m.p. 272°-273° C., δ (360 MHz, NAOD) 1.22 (3H, t, CH3), 3.41 (2H, q, CH2), 6.65 (1H, s. 3-H), 7.18 (1H, d, 6-H), 7.54 (1H, t, 7-H), 7.68 (1H, d, 8-H), 11.94 (1H, s, NH), (Found: C, 65.97; H, 4.86; N, 6.72%, C12H11NO3 requires C, 66.35; H, 5.10; N, 6.45%).

Provenance & Evidence