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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 32661Erstellt: 25. Oktober 2026

1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone → 3-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-bromo benzonitrile

https://huagongshe.com/reaction/32661

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanoneHCID 685610—
Edukt2-Bromo-5-cyanobenzoic acidHCID 53256761—
Produkt3-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-bromo benzonitrileHCID 5979352149%

Reaktionsschritte

Title compound was prepared according to procedure described in example K/step2 from 1-(3-Fluoro-4-piperazin-1-yl-phenyl)-ethanone and 2-bromo-5-cyano-benzoic acid, (49% yield, white solid, MS (m/e): 430 (M+, 100%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07427612B2
Quelldatensatzuspto-grants-2008_09
ORD IDord-d5d5aa0a456a4044a6b254d0e42d7615
Quellennotizuspto-grants-2008_09