Sodium Hydroxide → 7-Ethenyl-4-oxo-1,4-dihydroquinoline-2-carboxylic acid

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Reaction Steps

Treatment of ethyl 7-ethenyl-4-oxo-1,4-dihydroquinoline-2-carboxylate (0.2 g) with sodium hydroxide (0.131 g), as described in Example 1c, gave 7-ethenyl-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (0.135 g), mp 281° C. (decomp.), δ (360 MHz, DMSO-d6), 5.47 and 6.00 (2H, 2d, =CH2), 6.61 (1H, s, 3-H), 6.84 (1H, 2d, CH=), 7.54 (1H, dd, 6-H), 7.94 (1H, d, 8-H), 8.05 (1H, d, 5-H) and 11.90 (1H, bs, NH), (Found: C, 63.76; H, 4.48; N, 6.12%, C12H9NO3. 0.6 H2O requires C, 63.77; H, 4.55; N, 6.20%).

Provenance & Evidence