3-Fluoroaniline → HCID 14842713, compound

Participants

Reaction Steps

Using the method described in Example 15 with 3-fluoroaniline (8.7 ml) and dimethylacetylene dicarboxylate (5.46 ml) gave 5-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (0.022 g), m.p. 285°-286° C. (dec), δ (360 MHz, NAOD) 6.86 (1H, s, 3-H), 7.04 (1H, m, 7-H) and 7.52-7.68 (2H. m, 6-H, 8-H).

Provenance & Evidence