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HRID326679

反应详情

EQUATION

反应方程式

HRID 326679 的结构方程式

REACTANTS

反应物

3
结构：NCCC(=O)O
HCID239

beta-Alanine

C3H7NO2

结构：O=C1CSC(=O)N1
HCID5437

Thiazolidinedione

C3H3NO2S

结构：COCCOCOc1c(C(C)(C)C)nc(C=O)nc1C(C)(C)C
HCID19922992

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)c1nc(C=C2SC(=O)NC2=O)nc(C(C)(C)C)c1O
HCID54264617

未命名化合物

收率 25%

PROCEDURE

实验过程

4,6-Bis-(1,1-dimethylethyl)-5-[(2-methoxyethoxy)methoxy]-2-pyrimidine carboxaldehyde (0.5 g, 1.5 mmoles) is treated with β-alanine (0.27 g, 3.1 mmoles) and 2,4-thiazolidinedione (0.22 g, 1.8 mmoles) according to the procedure of Example 6 to give 0.12 g (25%) of 5-[[4,6-bis-(1,1-dimethylethyl]-5 hydroxy-2-pyrimidinyl]methylene]-2,4-thiazolidinedione. MP=229°-232° C. dec.