4-Methylphenyl isocyanate → N-[[(4-methylphenyl)amino]carbonyl]-2-benzofuransulfonamide

HRID 326685Notes

Reaction equation

HRID 326685 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1[S:10]([NH2:13])(=[O:12])=[O:11].[CH3:14][C:15]1[CH:20]=[CH:19][C:18]([N:21]=[C:22]=[O:23])=[CH:17][CH:16]=1>>[CH3:14][C:15]1[CH:20]=[CH:19][C:18]([NH:21][C:22]([NH:13][S:10]([C:2]2[O:1][C:5]3[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=3[CH:3]=2)(=[O:11])=[O:12])=[O:23])=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 693254-Methylphenyl isocyanateHCID 107504321-Benzofuran-2-Sulfonamide

Product 1

HCID 21708724N-[[(4-methylphenyl)amino]carbonyl]-2-benzofuransulfonamideYield 63.7%

Procedure

2-Benzofuransulfonamide (7.6 mmol), prepared as described in Preparation 2, was reacted with 4-methylphenylisocyanate (7.6 mmol) as described in Preparation 2 to obtain 1.6 g of the title product as a solid.

Workup

  1. customas described in Preparation 2
  2. customas described in Preparation 2

Sources & evidence

ORD record
ord-46a5b4abb87d48ecbf829cc3c05b8fa7
Source dataset
uspto-grants-1993_12
Patent number
US05270329

Reaction notes

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