HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy3-oxoindan-1-carbonyl chloride → 1-(6-Methoxy-3-oxoindan-1-carbonyl)-2-(pyrrolidin-1-ylmethyl)piperidine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy3-oxoindan-1-carbonyl chloride | HCID 18915069 | — |
| Reactant | 2-(1-Pyrrolidinylmethyl)piperidine dihydrochloride | HCID 18915120 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 1-(6-Methoxy-3-oxoindan-1-carbonyl)-2-(pyrrolidin-1-ylmethyl)piperidine hydrochloride | HCID 18915036 | 36.5% |
Reaction Steps
From 1.21 g of 2-(pyrrolidin-1-ylmethyl)piperidine dihydrochloride. 1.35 g of 6-methoxy-3-oxoindan-1-carbonyl chloride and 2.79 ml of triethylamine. 0.72 g of the title compound was obtained, melting at 210°-228° C. (dec) using a procedure similar to that in Example 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270327 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-ef46843c6c4d44c2ab8c7ad3f22fff36 |
| Source note | uspto-grants-1993_12 |