HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-3-oxoindan-1-carbonyl chloride → 4-(5-Methyl-3-oxoindan-1-carbonyl)-3-(pyrrolidin-1-ylmethyl)morpholine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-3-oxoindan-1-carbonyl chloride | HCID 15730148 | — |
| Reactant | 3-(Pyrrolidin-1-ylmethyl)morpholine | HCID 18915061 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 4-(5-Methyl-3-oxoindan-1-carbonyl)-3-(pyrrolidin-1-ylmethyl)morpholine hydrochloride | HCID 18915090 | 15.3% |
Reaction Steps
The procedure described in Example 24 was repeated, but using 0.89 g of 3-(pyrrolidin-1-ylmethyl)morpholine, 2.2 ml of triethylamine and 0.83 g of 5-methyl-3-oxo-indan-1-carbonyl chloride, to afford 0.23 g of the title compound, melting at 225°-230° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270327 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-dc4388104a6d4a459f78bfdd53b5d90f |
| Source note | uspto-grants-1993_12 |