HuagongsheHuagongshe Chemistry Print Report · For research reference only
Gamma-Aminobutyric Acid → 4-Phthalimidobutyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Gamma-Aminobutyric Acid | HCID 119 | — |
| Reactant | Phthalic Anhydride | HCID 6811 | — |
| Product | 4-Phthalimidobutyric acid | HCID 18411 | 88.5% |
Reaction Steps
2 g of gamma-aminobutyric acid is reacted with an equimolar amount (2.87 g) of phthalic anhydride by dry melting at 150° C. The reaction product is crystallized from ethanol/water (1/2) so yielding 4 g of gamma-phthalimidobutyric acid with melting point 120°-123° C. and 88% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270338 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-684a47a5a1ab44f187bd750d09e195f4 |
| Source note | uspto-grants-1993_12 |