HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 5-(Propane-1-sulfonyl)-2-pyrrolidin-1-yl-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 2-Chloro-5-(propane-2-sulfonyl)benzoic acid | HCID 43140999 | — |
| Reactant | 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid | HCID 59793489 | — |
| Product | 5-(Propane-1-sulfonyl)-2-pyrrolidin-1-yl-benzoic acid | HCID 59793636 | 63% |
Reaction Steps
The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid from 2-Chloro-5-(propane-2-sulfonyl)-benzoic acid and pyrrolidine and obtained in 63% yield. MS (m/e): 296.2 (MH−, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427612B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-790179f33c32489cb60f0cda3d50b17c |
| Source note | uspto-grants-2008_09 |