Sodium Hydroxide → HCID 23718316, compound

HRID 326785Notes

Reaction equation

HRID 326785 reaction equation
[C:1]([NH:7][CH2:8][C:9]([O:11]CC)=[O:10])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].[OH-].[Na+:15]>CO>[C:1]([NH:7][CH2:8][C:9]([O-:11])=[O:10])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].[Na+:15]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 3622015HCID 3622015, compound

Product 1

HCID 23718316HCID 23718316, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of ethyl N-pivaloylglycinate (11.3 g) in 50 mL of methanol was added 69.2 mL of 1N sodium hydroxide, and the solution stirred for 2 hr. Solvents were evaporated in vacuo. Fresh methanol was added and reevaporated to give 12.45 g of off-white solid.

Workup

  1. customSolvents were evaporated in vacuo
  2. additionFresh methanol was added
  3. customreevaporated

Sources & evidence

ORD record
ord-fd5237fbfaf64574a660765d6bbb4bb7
Source dataset
uspto-grants-1993_12
Patent number
US05270331

Reaction notes

Loading…