Sodium Hydroxide → HCID 23718315, compound

HRID 326786Notes

Reaction equation

HRID 326786 reaction equation
[CH2:1]([CH:3]([CH2:13][CH3:14])[C:4]([NH:6][CH2:7][C:8]([O:10]CC)=[O:9])=[O:5])[CH3:2].[OH-].[Na+:16]>CO>[CH2:13]([CH:3]([CH2:1][CH3:2])[C:4]([NH:6][CH2:7][C:8]([O-:10])=[O:9])=[O:5])[CH3:14].[Na+:16]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 2268387ethyl 2-(2-ethylbutanoylamino)acetate

Product 1

HCID 23718315HCID 23718315, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of ethyl N-(2-ethylbutyryl)glycinate (33.73 g) in 100 mL of methanol was added 167.6 mL of 1N sodium hydroxide, and the solution stirred for 1.5 hr. Solvents were evaporated in vacuo, and then fresh methanol was added and evaporated to give 32.6 g of a pale yellow oil.

Workup

  1. customSolvents were evaporated in vacuo
  2. additionfresh methanol was added
  3. customevaporated

Sources & evidence

ORD record
ord-4e69deb7f80a40ca802f059a16d2cd57
Source dataset
uspto-grants-1993_12
Patent number
US05270331

Reaction notes

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