4-Piperidone → N-(4-piperidyl)-N'-(2-amino-2-methylpropyl)-1,2-ethanediamine

Participants

Role	Name	HCID	Charge
Reactant	4-Piperidone	HCID 33721	—
Reactant	N,N'-(2-amino-2-methylpropyl)ethylenediamine	HCID 10898752	—
Product	N-(4-piperidyl)-N'-(2-amino-2-methylpropyl)-1,2-ethanediamine	HCID 19736233	—

Reaction Steps

In a manner analogous to that described immediately hereinabove, by reacting N-(2-amino-2-methylpropyl)-1,2-ethanediamine with piperidin-4-one, it is reductively alkylated to yield N-(4-piperidyl)-N'-(2-amino-2-methyl-propyl)-1,2-ethanediamine; and, 2,2,6,6-piperidin-4-one is reductively alkylated to yield N-(2,2,6,6-tetramethyl-4-piperidyl)-N'-(2-amino-2-methylpropyl)-1,2-ethanediamine having the structure: ##STR15##

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05270471
Source dataset	uspto-grants-1993_12
ORD ID	ord-f60808e2c46e4c61b6f76bcf318f4c83
Source note	uspto-grants-1993_12