HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2-Methoxymethyl-4(3H)-pteridinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Aminopyrazine carboxamide | HCID 280292 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Methoxymethyl-4(3H)-pteridinone | HCID 135507022 | — |
Reaction Steps
Obtained using the procedure described in Example 1, starting with 11.7 g (0.085 mole) of 3-amino-2-pyrazinecarboxamide, 73.0 g (0.38 mole) of triethyl orthomethoxyacetate [prepared according to E. T. Stiller, U.S. Pat. No. 2,422,598; C.A. 1947, 41, 5904a] and 75 ml of acetic anhydride. Yld: 12.3 g (75%), m.p. 187°-189° C. (ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270465 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-2efa70dae48e40678b29a1b2d61e0afa |
| Source note | uspto-grants-1993_12 |