HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2-Acetoxymethyl-4(3H)-pteridinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Aminopyrazine carboxamide | HCID 280292 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Acetoxymethyl-4(3H)-pteridinone | HCID 135411161 | — |
Reaction Steps
Obtained using the procedure described in Example 1, starting with 5.3 g (0.038 mole) of 3-amino-2-pyrazinecarboxamide, 34.5 g (0.157 mole) of triethyl orthoacetoxyacetate and 34.5 ml of acetic anhydride. Refluxing time: 1 hour 45 minutes. Yld: 5.4 g (65%), m.p. 210°-212° C. (ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270465 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-b54cc92cbd144d00a1b4e5169937bab9 |
| Source note | uspto-grants-1993_12 |