2-(2,3-Dichlorophenoxy)acetamidine hydrochloride → 2-(2,3-Dichlorophenoxy)acetamidine

HRID 326835Notes

Reaction equation

HRID 326835 reaction equation
Cl.[Cl:2][C:3]1[C:13]([Cl:14])=[CH:12][CH:11]=[CH:10][C:4]=1[O:5][CH2:6][C:7]([NH2:9])=[NH:8]>[OH-].[Na+]>[Cl:2][C:3]1[C:13]([Cl:14])=[CH:12][CH:11]=[CH:10][C:4]=1[O:5][CH2:6][C:7]([NH2:9])=[NH:8]

Participants

3

Reactant 1

HCID 197362082-(2,3-Dichlorophenoxy)acetamidine hydrochloride

Product 1

HCID 105130432-(2,3-Dichlorophenoxy)acetamidine

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

8.0 g (0.031 mole) of 2-(2,3-dichlorophenoxy)-acetamidine hydrochloride are suspended in sodium hydroxide solution and extracted with chloroform. The organic extract is concentrated to dryness under reduced pressure. The solid residue is washed with hexane and dried; it is used in the next step without further purification. Yld: 6.7 g (98%), m.p. 104°-108° C.

Workup

  1. extractionextracted with chloroform
  2. extractionThe organic extract
  3. concentrationis concentrated to dryness under reduced pressure
  4. washThe solid residue is washed with hexane
  5. customdried
  6. customit is used in the next step without further purification

Sources & evidence

ORD record
ord-be7285dea65b44f5924b6d3038872f89
Source dataset
uspto-grants-1993_12
Patent number
US05270465

Reaction notes

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