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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 32684Generated: October 26, 2026

Morpholine → 5-(Methanesulfonyl)-2-(morpholin-4-yl)benzoic acid

https://huagongshe.com/reaction/32684

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acidHCID 59793489—
Product5-(Methanesulfonyl)-2-(morpholin-4-yl)benzoic acidHCID 2110031980%

Reaction Steps

The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid from 2-Chloro-5-(methane-2-sulfonyl)-benzoic acid and morpholine and obtained in 80% yield. MS (m/e): 284.1 (MH−, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07427612B2
Source datasetuspto-grants-2008_09
ORD IDord-63d3928adb354bd78f48a4a5a16ecc4e
Source noteuspto-grants-2008_09