HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethyl Acetate → 4-Amino-2-[(2,2,2-trifluoroethoxy)methyl]pteridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethyl Acetate | HCID 8857 | — |
| Edukt | 3-Aminopyrazine-2-carbonitrile | HCID 817699 | — |
| Edukt | 2-(2,2,2-Trifluoroethoxy)acetamidine | HCID 10583013 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 4-Amino-2-[(2,2,2-trifluoroethoxy)methyl]pteridine | HCID 10539187 | — |
Reaktionsschritte
Obtained using the procedure described in section c of Example 2, starting with 7.2 g (0.060 mole) of 3-amino-2-pyrazinecarbonitrile and 14.2 g (0.091 mole) of 2-(2,2,2-trifluoroethoxy)acetamidine in 230 ml of absolute ethanol. Refluxing time: 7 hours. Yld: 6.5 g (42%), m p. 145°-147° C. (ethyl acetate).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05270465 |
| Quelldatensatz | uspto-grants-1993_12 |
| ORD ID | ord-276bc173ceef417b98d7a35107a2fbe0 |
| Quellennotiz | uspto-grants-1993_12 |