反应详情

Obtained using the procedure described in section b of Example 9, starting with 17.5 g (0.0608 mole) of crude 4-amino-2-[(4-chlorophenoxy)methyl]pteridine in 1750 ml of 5% aqueous sodium hydroxide. Heating time: 1 hours 30 minutes under reflux. Yld: 8.7 g (50%), m.p. 267°-269° C. (ethanol/N,N-dimethylformamide).

1. customObtained
2. temperatureHeating time
3. temperature1 hours 30 minutes under reflux