Ammonia → 2-(4-Methoxyphenoxy)ethanimidamide

HRID 326856Notes

Reaction equation

HRID 326856 reaction equation
[CH3:1][O:2][C:3]1[CH:14]=[CH:13][C:6]([O:7][CH2:8][C:9](=[NH:12])OC)=[CH:5][CH:4]=1.[NH3:15]>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([O:7][CH2:8][C:9]([NH2:12])=[NH:15])=[CH:13][CH:14]=1

Participants

4

Reactant 2

HCID 222Ammonia2×HCID 10655467Methyl 2-(4-methoxyphenoxy)acetimidate

Product 1

HCID 106549552-(4-Methoxyphenoxy)ethanimidamide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

23.9 g (0.122 mole) of methyl 2-(4-methoxyphenoxy)acetimidate are added to a solution, maintained at 10° C., of 10.4 g (0.61 mole) of ammonia in 480 ml of absolute ethanol. The reaction mixture is left for 2 days at room temperature and the excess ammonia is then driven off with a stream of nitrogen. The solution obtained is used in the next step without further purification.

Workup

  1. customThe solution obtained
  2. customis used in the next step without further purification

Sources & evidence

ORD record
ord-83bc569192db41a28229e94f15f4fcf6
Source dataset
uspto-grants-1993_12
Patent number
US05270465

Reaction notes

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