HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 4-Amino-7-methoxy-2-(methoxymethoxymethyl)pteridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 2-(Methoxymethoxy)acetamidine | HCID 10534653 | — |
| Reactant | 3-Amino-5-chloropyrazine-2-carbonitrile | HCID 15618933 | — |
| Product | 4-Amino-7-methoxy-2-(methoxymethoxymethyl)pteridine | HCID 14880143 | — |
Reaction Steps
Obtained using the procedure described in section c of Example 2, starting with 11.2 g (0.0725 mole) of 3-amino-5-chloro-2-pyrazinecarbonitrile[prepared according to E. C. Taylor et al. 1975, 40, 2341] and the above solution of 2-(methoxymethoxy)acetamidine in methanol. Refluxing time: 5 hours. Yld: 13.2 g (72%), m.p. 193°-195° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05270465 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-e0e70fbfcc24468ba5e1243cfd8d358d |
| Source note | uspto-grants-1993_12 |