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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 326914Generated: November 1, 2026

Diethyl Carbonate → (4S)-4-(propan-2-yl)-1,3-oxazolidin-2-one

https://huagongshe.com/reaction/326914

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl CarbonateHCID 7766—
ReactantPotassium CarbonateHCID 11430—
ReactantL-ValinolHCID 640993—
Product(4S)-4-(propan-2-yl)-1,3-oxazolidin-2-oneHCID 7157133—

Reaction Steps

The title compound was prepared according to Evans, Mathre and Scott (J. Org. Chem., 50, 1830 (1985)) from (S)-(+)-2-amino-3-methyl-1-butanol and diethyl carbonate in the presence of K2CO3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05270324
Source datasetuspto-grants-1993_12
ORD IDord-24c17d6b5c5b4c5984d2353f919a525c
Source noteuspto-grants-1993_12