Sodium Hydroxide → HCID 67602509, compound

HRID 326939Notes

Reaction equation

HRID 326939 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8]([CH:12]=[CH:13][C:14]3[CH:15]=[C:16]([C@H:20]([S:33][CH2:34][C:35]([CH3:41])([CH3:40])[CH2:36][C:37]([OH:39])=[O:38])[CH2:21][CH2:22][C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=4[C:29]([OH:32])([CH3:31])[CH3:30])[CH:17]=[CH:18][CH:19]=3)=[N:9]2)=[CH:4][CH:3]=1.[OH-].[Na+:43]>C(O)C>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8]([CH:12]=[CH:13][C:14]3[CH:15]=[C:16]([C@H:20]([S:33][CH2:34][C:35]([CH3:41])([CH3:40])[CH2:36][C:37]([O-:39])=[O:38])[CH2:21][CH2:22][C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=4[C:29]([OH:32])([CH3:30])[CH3:31])[CH:17]=[CH:18][CH:19]=3)=[N:9]2)=[CH:4][CH:3]=1.[Na+:43]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53656255HCID 53656255, compound

Product 1

HCID 67602509HCID 67602509, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of the acid of Step 11 in ethanol was added 1.0 equiv of 1N NaOH. The solvent was evaporated and the remaining oil was dissolved in water and freeze-dried to yield the title compound.

Workup

  1. customThe solvent was evaporated
  2. dissolutionthe remaining oil was dissolved in water
  3. customfreeze-dried

Sources & evidence

ORD record
ord-c1918d2009dd44e6af8decdf01b82cea
Source dataset
uspto-grants-1993_12
Patent number
US05270324

Reaction notes

Loading…