HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl piperazine-1-carboxylate → 4-(2-Fluoro-4-methyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | 4-Bromo-3-fluorotoluene | HCID 573280 | — |
| Product | 4-(2-Fluoro-4-methyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester | HCID 59793581 | 40% |
Reaction Steps
Title compound was prepared according to the procedure described in example G from N-Boc-piperazine and 4-bromo-3-fluorotoluene (40% yield, yellow oil, MS (m/e): 295.2 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427612B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-a1062e2ce66f4e638a2eee79416bf783 |
| Source note | uspto-grants-2008_09 |