4-Iodotoluene → 4,4'-Ditolylaminobenzophenon

Participants

Reaction Conditions

Reaction Steps

4.4 g of 4,4'-diaminobenzophenon, 30.9 g of P-iodotoluene, 19.5 g of potassium carbonate anhydride and 10 g of copper powder were added to 70 ml of o-dichlorobenzene, and the mixture thus obtained was refluxed with stirring for twenty-four hours at 180° C. After the reaction, the mixture was filtered and washed with ethyl acetate. Then, the mixture was separated by silica gel column chromatography using chloroform, thereby obtaining 11.3 g of 4,4'-ditolylaminobenzophenon.

Provenance & Evidence