Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Melatonin | HCID 896 | — |
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-Iodomelatonin | HCID 115348 | — |
Reaction Steps
To a solution of melatonin (2.32 g: 10 mM) in chloroform (70 ml) cooled at -20° C. there is added N-iodosuccinimide (NIS:2.25 g; 10 nM); the reaction mixture is stirred at -20° C. for 4.5 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05272141 |
|---|
| Source dataset | uspto-grants-1993_12 |
|---|
| ORD ID | ord-0f931396061d40c0820e9436235af492 |
|---|
| Source note | uspto-grants-1993_12 |
|---|
