HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Morpholin-4-yl-5-nitro-benzoyl chloride → [4-(2-Chloro-4-trifluoromethyl-phenyl)-piperazin-1-yl]-(2-morpholin-4-yl-5-nitro-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Morpholin-4-yl-5-nitro-benzoyl chloride | HCID 17274153 | — |
| Reactant | 1-[2-Chloro-4-(trifluoromethyl)phenyl]piperazine | HCID 46837496 | — |
| Product | [4-(2-Chloro-4-trifluoromethyl-phenyl)-piperazin-1-yl]-(2-morpholin-4-yl-5-nitro-phenyl)-methanone | HCID 59793524 | — |
Reaction Steps
The title compound was prepared according to the procedure described for example 46 from 1-(2-Chloro-4-trifluoromethyl-phenyl)-piperazine and 2-Morpholin-4-yl-5-nitro-benzoyl chloride (74%, yellow solid, MS (m/e): 499.2 (M+H, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427612B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-c34b2430246247cfb9fb1feab3edbe77 |
| Source note | uspto-grants-2008_09 |