2-Morpholin-4-yl-5-nitro-benzoyl chloride → HCID 59793603, compound

HRID 32706Notes

Reaction equation

HRID 32706 reaction equation
[F:1][C:2]([F:17])([F:16])[O:3][C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[CH:6][CH:5]=1.[N:18]1([C:24]2[CH:32]=[CH:31][C:30]([N+:33]([O-:35])=[O:34])=[CH:29][C:25]=2[C:26](Cl)=[O:27])[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1>>[N:18]1([C:24]2[CH:32]=[CH:31][C:30]([N+:33]([O-:35])=[O:34])=[CH:29][C:25]=2[C:26]([N:13]2[CH2:12][CH2:11][N:10]([C:7]3[CH:8]=[CH:9][C:4]([O:3][C:2]([F:1])([F:16])[F:17])=[CH:5][CH:6]=3)[CH2:15][CH2:14]2)=[O:27])[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 172741532-Morpholin-4-yl-5-nitro-benzoyl chlorideHCID 230811701-(4-(Trifluoromethoxy)phenyl)piperazine

Product 1

HCID 59793603HCID 59793603, compound

Procedure

The title compound was prepared according to the procedure described for example 46 from 1-(4-Trifluoromethoxy-phenyl)-piperazine and 2-Morpholin-4-yl-5-nitro-benzoyl chloride (74%%, yellow solid, MS (m/e): 481.2(M+H, 100%)

Sources & evidence

ORD record
ord-46e076917c9e40fcb0f29e2c4b4576ef
Source dataset
uspto-grants-2008_09
Patent number
US07427612B2

Reaction notes

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