Oxalyl chloride → 5-Acetyl-2-ethoxybenzoyl chloride

関与物質

反応手順

Oxalyl chloride (3.66 g, 0.029 mol) was added dropwise to a stirred solution of 5-acetyl-2-ethoxybenzoic acid (3.0 g, 0.014 mol) in dichloromethane (15 ml) and dimethylformamide (0.1 ml) After 3 hours at room temperature, the solvent was removed by evaporation under vacuum and the residue axeotroped with hexane (3×30 ml) to give the title compound, which was used without further purification.

情報源と証拠