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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 32711Generated: October 25, 2026

Piperazin-4-ylacetophenone → 1-{4-[4-(2-Fluoro-5-nitro-benzoyl)-piperazin-1-yl]-phenyl}-ethanone

https://huagongshe.com/reaction/32711

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazin-4-ylacetophenoneHCID 97269—
Reactant2-Fluoro-5-nitrobenzoic acidHCID 280997—
Product1-{4-[4-(2-Fluoro-5-nitro-benzoyl)-piperazin-1-yl]-phenyl}-ethanoneHCID 59793540—

Reaction Steps

The title compound was prepared according to the procedure described for example K step 2 from 4′-piperazino-acetophenone and 2-fluoro-5-nitrobenzoic acid (16%, yellow solid, MS (m/e): 372.1 (M+H, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07427612B2
Source datasetuspto-grants-2008_09
ORD IDord-5fe5988acc124388af11684098b37d86
Source noteuspto-grants-2008_09