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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 327129Generated: October 26, 2026

Phenethylamine → N-cyano-N'-(2-phenylethyl)-3-quinolinecarboximidamide

https://huagongshe.com/reaction/327129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenethylamineHCID 1001—
ReactantMethyl N-cyano-3-quinolinecarboximidateHCID 10058988—
SolventMethanolHCID 887—
ProductN-cyano-N'-(2-phenylethyl)-3-quinolinecarboximidamideHCID 1973457891%

Reaction Steps

Methyl N-cyano-3-quinolinecarboximidate (0.32 g, 1.5 mmol) was dissolved in methanol (3 ml), 2-phenylethylamine (0.20 g, 1.65 mmol) was added. The mixture was stirred at room temperature for 30 minutes After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was crystallized from diethyl ether to give the title compound (0.41 g, 1.36 mmol, yield: 91%) as pale yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05272164
Source datasetuspto-grants-1993_12
ORD IDord-661085d5f084441392da0d0ef2776e78
Source noteuspto-grants-1993_12