HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 18921818, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | 2,4-Dichlorophenol | HCID 8449 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18921818 | HCID 18921818 | — |
Reaction Steps
Add imidazole (25 g) and NaOH (15 g) to DMF (250 ml) and stir for I hour. Add the product of part (a) (8.65 g) and stir overnight. Evaporate the solvent, partition the resultant residue with water/dichloromethane (adjust aqueous layer to pH 7 with potassium phosphate), separate organic layer and evaporate solvent. Purify the resultant residue on a silica column to obtain the title compound, MS: m/z 295 (M+ +1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05272167 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-1b70fd0c797045208b0336103fefa309 |
| Source note | uspto-grants-1993_12 |