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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 32723Generated: October 25, 2026

1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone → 1-{3-Fluoro-4-[4-(5-methylsulfanyl-2-morpholin-4-yl-benzoyl)-piperazin-1-yl]-phenyl}-ethanone

https://huagongshe.com/reaction/32723

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanoneHCID 685610—
Reactant5-Methylsulfanyl-2-morpholin-4-yl-benzoic acidHCID 59793576—
Product1-{3-Fluoro-4-[4-(5-methylsulfanyl-2-morpholin-4-yl-benzoyl)-piperazin-1-yl]-phenyl}-ethanoneHCID 59793498—

Reaction Steps

The title compound was prepared according to the procedure described for example K step 2 from 5-Methylsulfanyl-2-morpholin-4-yl-benzoic acid and 1-(3-Fluoro-4-piperazin-1-yl-phenyl)-ethanone (8%, white solid), MS (m/e): 458.2 (M+, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07427612B2
Source datasetuspto-grants-2008_09
ORD IDord-b02c760935464a53870c03379f4ddb4d
Source noteuspto-grants-2008_09