Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 32729Generated: October 25, 2026

1-(2,4-Difluorophenyl)piperazine → [4-(2,4-Difluoro-phenyl)-piperazin-1-yl]-(2-morpholin-4-yl-5-nitro-phenyl)-methanone

https://huagongshe.com/reaction/32729

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,4-Difluorophenyl)piperazineHCID 2734637—
Reactant2-Morpholin-4-yl-5-nitro-benzoyl chlorideHCID 17274153—
Product[4-(2,4-Difluoro-phenyl)-piperazin-1-yl]-(2-morpholin-4-yl-5-nitro-phenyl)-methanoneHCID 59793560—

Reaction Steps

The title compound was prepared according to the procedure described for example 46 from 2-Morpholin-4-yl-5-nitro-benzoyl chloride and 1-(2,4-difluorophenyl)-piperazine (87%, yellow solid, MS (m/e): 433.4 (M+H, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07427612B2
Source datasetuspto-grants-2008_09
ORD IDord-45cbfa89a1214440887e0954c82bdca7
Source noteuspto-grants-2008_09