HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → rel-(4R,5S)-4,5-bis(3'-benzyloxy-4'-methoxyphenyl)oxazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | rel-(1S,2R)-1,2-bis(3'-Benzyloxy-4'-methoxyphenyl)-2-aminoethanol | HCID 22849455 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | rel-(4R,5S)-4,5-bis(3'-benzyloxy-4'-methoxyphenyl)oxazolidin-2-one | HCID 15011034 | — |
Reaction Steps
Mixture: 1.0 g (2.06 mmol) of rel-(1S,2R)-1,2-bis(3'-benzyloxy-4'-methoxyphenyl)-2-aminoethanol, 334 mg (2.05 mmol) of carbonyldiimidazole, 20 ml of toluene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05272270 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-7c245ae600964402b67dc6817f5de098 |
| Source note | uspto-grants-1993_12 |