HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1,1-dimethoxyethane → rel-(1S,2R)-1,2-bis(3'-Benzyloxy-4'-methoxyphenyl)-2-[(2",2"-dimethoxyethyl)-methyl-amino]ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1,1-dimethoxyethane | HCID 81672 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | rel-(1S,2R)-1,2-bis(3'-benzyloxy-4'-methoxyphenyl)-2-methylaminoethanol | HCID 22849456 | — |
| Product | rel-(1S,2R)-1,2-bis(3'-Benzyloxy-4'-methoxyphenyl)-2-[(2",2"-dimethoxyethyl)-methyl-amino]ethanol | HCID 11813953 | — |
Reaction Steps
Mixture: 1.40 g 2.8 mmol) of rel-(1S,2R)-1,2-bis(3'-benzyloxy-4'-methoxyphenyl)-2-methylaminoethanol, 0.43 ml (0.61 g, 3.6 mmol) of bromoacetaldehyde dimethyl acetal, 0.71 g (8.4 mmol) of sodium hydrogen carbonate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05272270 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-e484ae2d2c62411594c1dae5bb0026aa |
| Source note | uspto-grants-1993_12 |