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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 327416Generated: October 30, 2026

Water → N-[4-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)1-butynyl]phenyl]acetamide

https://huagongshe.com/reaction/327416

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantAcetyl chlorideHCID 6367—
Reactant4-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)but-1-ynyl]anilineHCID 10425024—
ProductN-[4-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)1-butynyl]phenyl]acetamideHCID 19960136—

Reaction Steps

The title compound is prepared from 4-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl-1-butynyl]benzenamine (Example 14) and acetyl chloride, containing 0.1 mol of water; mp 172°-173.4° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05273977
Source datasetuspto-grants-1993_12
ORD IDord-89ec985a0b874002b7234661388790f0
Source noteuspto-grants-1993_12