HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 5-Methanesulfonyl-2-piperidin-1-yl-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2-Chloro-5-(methylsulphonyl)benzoic acid | HCID 2329132 | — |
| Reactant | 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid | HCID 59793489 | — |
| Product | 5-Methanesulfonyl-2-piperidin-1-yl-benzoic acid | HCID 21806157 | 78% |
Reaction Steps
The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid (Example Y) from 2-Chloro-5-methanesulfonyl-benzoic acid and piperidine and obtained in 78% yield. MS (m/e): 282.0 (M−H+ 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427612B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-935b65ad7fd84fc8a890dce16625d121 |
| Source note | uspto-grants-2008_09 |