HCID 19108632, compound → HCID 19108635, compound

Participants

Reaction Steps

A solution of N-(N',N'-dimethylamino)-1-methyl-4-[1-methyl-4-nitroimidazole-2-carboxamido]-imidazole-2-carboxamide (0.50 g, 1.49 mmol) and 5% Pd on charcoal (0.2 g) in chilled methanol (20 mL) was purged of air and hydrogenated at room temperature for 6 hours. The catalyst was removed by filtration and the methanol evaporated under reduced pressure to give N-(N',N'-dimethylamino)-1-methyl-4-[1-methyl-4-aminoimidazole-2-carboxamido]-imidazole-2-carboxamide as an unstable yellow solid.

Provenance & Evidence