HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 327448Generated: October 26, 2026
Ammonia → 3-Chloro-2-methyl-6-nitroaniline
https://huagongshe.com/reaction/327448
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 2,6-Dichloro-3-nitrotoluene | HCID 97155 | — |
| Product | 3-Chloro-2-methyl-6-nitroaniline | HCID 12953020 | 76% |
Reaction Steps
A suspension of 2,6-dichloro-3-nitrotoluene (6.0 g, 29 mmol) in 50% methanolic ammonia (60 mL) was stirred at 130° C. (340 lb pressure) for 18 hours. The autoclave was cooled to -30° C., opened, and the precipitate was filtered off and washed with methanol to give 4.14 g (76%) of 3-chloro-2-methyl-6-nitrobenzenamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05273975 |
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| Source dataset | uspto-grants-1993_12 |
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| ORD ID | ord-6a783ee54f534c5382fab3da4c85a8fe |
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| Source note | uspto-grants-1993_12 |
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